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[FlowCAM] FlowCAM을 이용한 Microencapsulation 과정 분석
작성자 : 삼보과학   작성일 : 2011-04-28   조회수 : 4353
파일첨부 : Microencaps_App_Note_200ppi[1].pdf
Microencapsulation Process Analysis Using FlowCAM
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Objective

Microencapsulation is a pervasively used technique for delivering particles in a wide range of applications, ranging from pharmaceuticals to foods to detergents. Microencapsulation is a process by which small amounts of a substance (active ingredient) are packaged inside a second substance in order to shield the active ingredient from the surrounding environment.
The first large-scale application of microencapsulation dates back to the 1950’s, when National Cash Register (NCR) used complex coacervation to produce carbonless copy paper. However, despite the long history and myriad uses of microencapsulation, the technique remains both a science and an art due to the fact that each microencapsulation application can require new materials and methods to be used. Because of this, the ability to study microencapsultion at a microscopic level is critical for the understanding and development of new processes.
Imaging particle analysis using FlowCAM® offers an ability to gain unique insights into the microencapsulation process by being able to dynamically monitor capsule formation over time while studying the effects of temperature, concentration, pH and other variables that affect the process. Complex coacervation, whereby microcapsules are formed by combining two hydrocolloids to produce a shell around droplets of the active ingredient (usually in an emulsion) is a common technique which can greatly benefit from FlowCAM monitoring. This is a complex process, and the insight from FlowCAM can be invaluable.

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